The More-than-Human (MtH) turn represents a shift from user-centred to relational-centred design, recognising humans, nonhumans, and technologies as interconnected agents within a complex system. This post-anthropocentric reorientation calls for the ongoing exploration of design practices that engage more-than-human entanglements. This paper investigates how the chemical senses, specifically and taste, can act as relational agents in supporting the practice of “decentring” within the MtH design framework. We introduce the concept of “Sensing the Other” (StO) as a strategic approach to designing with the chemical senses, proposing that olfactory and gustatory modalities can reveal and mediate the porous boundaries between MtH design components. Our exploratory study draws on two previous studies: (1) the development of a multisensory Human-Computer Interaction (HCI) design strategy incorporating the chemical senses to support public communication on environmental health, and (2) a follow-up study assessing the strategy’s effectiveness from the perspective of key stakeholders. The findings suggest that integrating chemical senses enhance awareness, fosters embodied sense-making, and stimulates innovation. Building on these insights, we present two speculative design scenarios that illustrate how olfactory and gustatory experiences can engage multispecies relations and enrich MtH design. We argue that the inclusion of the chemical senses offers valuable material and epistemological contributions to MtH design framework. Ultimately, this study contributes to the emerging MtH design paradigm and advances the field of multisensory HCI in the context of environmental health communication.