Industry 5.0 technologies are becoming increasingly popular in different industries, and the new era of industrial innovation is on the horizon when people, collaboration, and innovative technology will be united in human creativity, cooperation, and the use of such technologies as AI, IoT, robotics, and digital twins. Although still at its infant level, Industry 5.0 is already showing deep effects in industries like manufacturing, healthcare, agriculture and smart cities. The main goal of the chapter is to discuss the industrial applications of the technologies of Industry 5.0 in the real world, paying attention to the innovative companies and industry-related stories of implementation where the power of the new industrial revolution based on humanism is observed. Through the study of successful case studies, we will be able to point out the strategies that have made them successful, the lessons they have learnt and the challenges they have encountered in the process. This chapter is very informative to organizations that want to implement and expand industry 5.0, solutions and the barriers that usually come along with such a revolutionary change.