The research explores opportunities to enhance state regulation of smart transport systems within the digital economy infrastructure to strengthen Russia’s economic security. Using regression analysis, the authors synthesize best practices from the top 15 countries with the most advanced smart transport systems as of 2025. The research clarifies the contribution of AI and IoT technologies and the quality of transport and logistics infrastructure to national economic security. The authors identify limitations in the ability of regulatory procedures for smart transport systems to directly influence key economic indicators such as trade balance, the ratio of national debt to GDP, and GDP growth rates. The research also finds that the automation of transport logistics has minimal impact on certain aspects of economic security, such as the growth of business confidence and the rise in stock market value. Conversely, the research highlights key indicators of national economic security that are significantly and directly influenced by the regulation of smart transport systems, including increased business activity in the manufacturing sector and rising consumer trust in domestic product brands. The research outlines prospects and offers original recommendations for developing smart transport systems in Russia’s digital economy infrastructure through 2030, focusing on leveraging IoT technologies.