The Transgender community across the world face discrimination from all walks of life. The transgender, even if educated and skilled, faces multiple hurdles during the employment process and within the workplace once employed. The challenges have even increased with COVID-19 and mass layoffs affecting employees across the globe. Transgender people have to be empowered to face the challenges of employment processes and workplace challenges as and when they arise. With the advancement of digital technologies, the Fourth Industrial Revolution can be leveraged for training, empowerment, awareness, network building, grievance redressal and sustainability for the transgender community. Digital technologies leverage the community to collaborate and be vocal about their needs and rights at a global level. Digital technology also helps the transgender community reach the proper forum to implement the required program for the benefit of the community. The decentralized and anonymous system for recording data and reporting incidents will also be a helpful, transparent process without being subject to unnecessary scrutiny. The technology-enabled system and practices will also help the companies and institutions to ascertain appropriate and efficient methods for creating gender gender-neutral environment devoid of any discrimination. Recently, there was a significant rise in concerns about employment practices for the LGBTQ community around the globe during the pandemic, such as lockdown protocols affecting employment conditions, vaccine access, support from employers, severance pay, mental health, etc. The International ecosystem has seen minimal regulatory discussion, and individual countries and companies are now implementing schemes to address the issue faced by transgender individuals in the employment and work ecosystem through the infusion of technologies.