This chapter examines the fundamental transformation in neuroscience-public engagement. This chapter argues for a shift from traditional “deficit model” approaches that treat science communication as simple knowledge transfer toward sophisticated participatory frameworks that recognize diverse audiences as active partners rather than passive recipients. The analysis demonstrates how the historic deficit model has evolved significantly. This model assumed public skepticism stemmed from knowledge gaps requiring expert education. It has evolved through dialogical approaches emphasizing two-way communication toward participatory models where communities become genuine collaborators in research processes. This chapter addresses unique challenges facing neuroscience communication. These include the persistence of “neuromyths” (widespread misconceptions about brain function) and ethical complexities arising when research touches on fundamental questions of human identity, consciousness, and personal responsibility. These challenges intensify as neuroscience increasingly intersects with artificial intelligence. Through a comprehensive examination of evidence-based engagement strategies, this chapter explores participatory research methods, narrative approaches that help audiences connect emotionally with research significance, and visual communication techniques that make complex concepts accessible without oversimplification. Special attention is given to artificial intelligence applications for personalizing science communication while maintaining scientific integrity through careful boundary setting around which content elements can be adapted versus which must remain consistent across audiences. The analysis demonstrates how trust-building through transparency—including acknowledgment of research limitations and uncertainties—actually strengthens rather than undermines public confidence while examining how scientists can communicate controversial topics by framing research in terms of shared values without compromising scientific accuracy. This chapter concludes by exploring the evolving role of scientists as public communicators, showing how communication skills are increasingly recognized as core scientific competencies rather than optional outreach activities while helping researchers navigate complex boundaries between scientific expertise and public advocacy in an era where neuroscience findings have profound implications for social policy and human self-understanding.