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Chapter 4 presents an overview of analytical strategies for the identification and quantification of cannabinoids across diverse matrices. It begins by addressing sample preparation requirements for plant materials, cannabis-derived products, and biological samples, emphasizing how matrix complexity influences analytical accuracy and reliability. The chapter then examines the main separation techniques used in cannabinoid analysis, including gas chromatography, liquid chromatography, and supercritical fluid chromatography, highlighting their principles, strengths, and limitations. Complementary and emerging techniques are also introduced to provide a broader analytical perspective. By linking sample preparation with appropriate analytical methods, this chapter guides readers in selecting robust, fit-for-purpose approaches for research, quality control, regulatory compliance, and pharmacokinetic studies in the rapidly evolving cannabinoid field.

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Analytical Techniques for Identification and Quantification of Cannabinoids

  • 章节

  • 发表日期：

    2026年

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  • Shahnshah E. Azam,
  • Luís Loureiro,
  • António A. Vicente,
  • Renata Vardanega

摘要

Chapter 4 presents an overview of analytical strategies for the identification and quantification of cannabinoids across diverse matrices. It begins by addressing sample preparation requirements for plant materials, cannabis-derived products, and biological samples, emphasizing how matrix complexity influences analytical accuracy and reliability. The chapter then examines the main separation techniques used in cannabinoid analysis, including gas chromatography, liquid chromatography, and supercritical fluid chromatography, highlighting their principles, strengths, and limitations. Complementary and emerging techniques are also introduced to provide a broader analytical perspective. By linking sample preparation with appropriate analytical methods, this chapter guides readers in selecting robust, fit-for-purpose approaches for research, quality control, regulatory compliance, and pharmacokinetic studies in the rapidly evolving cannabinoid field.