This chapter explores the ethical and legal considerations underpinning the deployment of AI in healthcare. Rather than narrowing the discussion to specific applications such as facial trauma or oral-systemic health, the chapter addresses foundational principles–such as fairness, transparency, accountability, data privacy, and informed consent–that are universally relevant across all domains of healthcare AI. By presenting these overarching ethical and legal concepts, the chapter provides readers with a framework applicable to current and emerging AI systems. This broad approach ensures adaptability and foresight, enabling responsible innovation as healthcare AI evolves across diverse clinical, diagnostic, and public health contexts.