This chapter explores the potential of AI in addressing the challenges faced by school leadership and management in the Global South. The chapter highlights how AI can foster collaboration, improve data use, and support instructional leadership, thereby enhancing school effectiveness. It examines current AI applications in administrative automation, data-driven decision-making, and resource optimization, while also addressing ethical considerations around data privacy, algorithmic bias, and equitable access. The discussion emphasizes the need for AI to amplify human judgment and support participatory leadership, ultimately aiming to create more resilient, equitable, and human-centered school systems.