This study investigates the relationships between Information Technology (I.T.) performance, I.T. managerial resources, social responsibility, strategic alignment, sustainable competitive advantage, and trust on economic business performance in small and medium-sized enterprises (SMEs) using quantitative methods and structural equation modeling. Findings reveal the pivotal role of strategic alignment and sustainable practices in mediating the connections between values, beliefs, I.T. resources, and sustainable competitive advantage, emphasizing the importance of aligning business strategies with organizational goals and values for enhanced competitive positioning and long-term performance sustainability. The study highlights that integrating social responsibility initiatives into strategic planning can improve an organization’s reputation, enhance trust, and positively contribute to society and the environment. Recommendations include fostering a culture that supports sustainable practices and prioritizing long-term value creation. Future research could explore industry-specific settings, external factors such as economic or regulatory environments, and their impacts on sustainable competitive advantage. These insights provide organizations with a roadmap to navigate the complexities of modern business landscapes and achieve sustainable success.