Interprofessional collaboration aims to address some of the current challenges faced in neurology practice, such as the increasing number of people with neurological conditions, the shortage of neurologists and other health professionals, and fragmented health systems. The number and types of professions in neurology multidisciplinary teams vary based on the disease, disease stage, clinical setting, and resources. Key related health professions include first line of contact and primary care workers, nurses, case coordinators, social workers, therapists, psychologists, pharmacists, dieticians, nutritionists, and interpreters. Several pillars are essential to establishing interprofessional collaboration. Interprofessional curricula educate health workers about other team members, how to best work as a team, and how to maximize individual skills and knowledge. Additionally, interprofessional collaboration requires organizational, legislative, economic, and logistic support, as well as quality research to develop evidence-based best interprofessional collaborative practices (ICPs). Successful ICP requires shared and unifying goals, based on optimal patient care, clear roles, mutual trust and respect, and collective leadership. ICP models include inpatient stroke units, integrated care models for managing chronic diseases, and interprofessional clinics for a spectrum of clinical needs. Different ICP models should be adapted to local needs and resources, which also makes creating a best practice guideline challenging due to funding and time limitations. However, leveraging digital and new technologies can help with scale and access. Identifying approaches to effectively collaborate with different health professions to deliver neurology care is crucial to improve patient access and health outcomes.