The growth of the world population has caused an increase in agricultural activities to satisfy the demand for food. For which it is necessary to apply different agrochemicals as fertilizers, pesticides, herbicides and fungicides. However, this has caused a various hazardous pollutant, such as heavy metals and persistent organic pollutants to accumulate in agricultural soils. These substances are mainly derived from anthropogenic sources, mainly industrial, agricultural and urban. Agricultural soils have been reported to be highly contaminated with heavy metals, derived from various sources such as fertilizer application, pesticides, wastewater irrigation, mining and natural sources. Studies of soils contaminated with persistent organic pollutants have also been reported. This represents an urgent problem because these substances can enter the food chain as they are absorbed through plants and can ultimately affect human health. The presence of these contaminants has been detected in human samples such as blood and breast milk. Long-term exposure to pollutants related to agricultural soils has been associated with several serious health problems. It is therefore crucial to implement effective management and rehabilitation strategies for contaminated agricultural soils. This includes regular monitoring of soil quality, promotion of sustainable agricultural practices, reduction of the use of hazardous chemicals, and rehabilitation of degraded land.