Industrial networks are becoming increasingly complex due to rising connectivity demands, real-time requirements, and cross-domain integration challenges. These changes require efficient and adaptive configuration and management solutions. State-of-the-art tools depend on manual configurations or rigid rule-based automation, limiting scalability and responsiveness. This paper presents a Flow-Based Programming (FBP) approach using Node-RED to enable flexible, event-driven network automation. By integrating Information Technology (IT) and Operational Technology (OT) components, our framework enhances both security and operational safety, reduces manual intervention, and ensures consistent policy enforcement. We demonstrate its effectiveness through two industrial use cases—automated port lockdown for secure access control and automated software updates for Automated Guided Vehicles (AGVs), showcasing its potential to streamline network management and reduce operational downtime.