Energy-efficient ventilation and indoor climate control technologies are crucial for achieving zero-energy and zero-emission buildings, as they account for 38% of the total energy consumption in buildings worldwide. In this context, research has focused on developing an adaptive and integrated envelope technology connected to building ventilation systems, aiming to reduce heating consumption by harnessing solar energy through intelligent control. The system developed comprises a modular transventilated solar façade, an integrated control system that ensures optimal energy management of the building’s air intake, and fault detection capabilities. This study involves validating the complete system, connected to the air handling unit installed in Tecnalia’s K2 experimental infrastructure located in Derio, Spain. The experimental approach includes characterizing the thermal performance of the façade under local climatic conditions and evaluating automated control strategies that consider the building’s ventilation and thermal requirements. A comprehensive analysis is conducted to assess the suitability of such systems in the current climate zone and the potential energy savings.