In this paper, we propose a new structure for the SQIsign family: Pentagon Isogeny-based Signature in High Dimension (referred to as PIsignHD). The new structure separates the hash of the commitment and that of the message by employing two cryptographic hash functions. This feature is desirable in reality, particularly for applications based on mobile low-power devices or for those deployed interactively over the Internet or in the cloud computing setting. This structure can be generally applied to all SQIsign variants. In this work, we focus on the instance based on SQIsignHD. Compared with SQIsignHD, PIsignHD has the same signature size (even smaller for some application scenarios). For the NIST-I security level, the signature size of PIsignHD can be reduced to 519 bits, while the SQIsignHD signature takes 870 bits. Additionally, PIsignHD has an efficient online signing process and enjoys much desirable application flexibility. In our experiments, the online signing process of PIsignHD runs in 4 ms.