Spirituality reflects how a person relates to life’s deepest questions—its meaning, purpose, and connection to something greater than oneself. To ignore a patient’s spiritual beliefs is to overlook a vital part of who they are. This chapter explores how to recognize and support your patients’ spiritual needs with respect and sensitivity. It introduces the FICA tool—a practical framework for taking a spiritual history and understanding how beliefs may influence health, coping, and decision-making. We’ll examine your role as a healthcare provider in addressing spiritual concerns, offering compassionate support, and integrating these conversations into patient care. The chapter also includes a real patient story that illustrates how acknowledging and honoring a patient’s spirituality can profoundly shape the healing process.