This chapter deepens the Sensible Design framework by applying it to additional sensory and functional dimensions. It introduces a multi-layered approach to zoning—including sensory zoning, compartmentalization, arrangeable furniture, and rospect and refuge strategies—offering solutions tailored to diverse sensory profiles, priorities, and preferences that promote autonomy and inclusivity while balancing stimulation and regulation. It exhamines comfort and restoration through design features such as biophilic integration, ergonomic and tactile comfort, thermal regulation, and olfactory management. Safety is reframed through a sensory lens, highlighting the importance of staff training, emergency preparedness, and emotionally secure environments. Building on Chap. 3 , the framework presents sensory-specific, threshold-responsive design strategies that enhance both accessibility and well-being. These interventions are explicitly aligned with UD principles and mapped across baseline, low-threshold, and high-threshold users. The chapter integrates several real-world examples and illustrations and offers practical design prompts applicable across diverse environments. It advances a compelling case for design that is both sensorially attuned and functionally adaptable, underscoring that true inclusion goes beyond compliance to promote dignity, agency, belonging and well-being.