Non-neurogenic daytime urinary incontinence in children can be simplified by determining if the patient has an overactive bladder or dysfunctional voiding. A detailed voiding history, voiding diary, and post-void residual are the key tools in the diagnosis. Nocturnal enuresis is due to an interplay of fluid intake, bladder capacity, and the ability to sense a full bladder while sleeping. Both behavioral and pharmacologic treatments should be chosen based on the underlying cause for the daytime or night-time urinary incontinence.