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This paper presents a comprehensive approach to understanding cardiovascular dynamics by implementing a model based on the Windkessel concept. The model addresses vascular compliance and peripheral resistance, essential aspects of cardiovascular physiology. Simulations demonstrate the model’s ability to represent the interaction between these critical parameters dynamically. The methodology is based on formulating a differential equation that describes the relationship between blood pressure and blood flow, inspired by the Windkessel model. Additionally, a differential evolution algorithm was developed to adjust model parameters. Simulation is used to explore the model’s sensitivity and to obtain dynamic profiles of vascular compliance and peripheral resistance. Clinical implications and future work are discussed.

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Evolutionary Parametric Identification for Arterial Hypertension with a Non-linear Model

  • 会议论文

  • 发表日期：

    2026年

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  • Pedro M. Gomez,
  • Alma Y. Alanis,
  • Oscar D. Sanchez,
  • Karen A. Quiroz

摘要

This paper presents a comprehensive approach to understanding cardiovascular dynamics by implementing a model based on the Windkessel concept. The model addresses vascular compliance and peripheral resistance, essential aspects of cardiovascular physiology. Simulations demonstrate the model’s ability to represent the interaction between these critical parameters dynamically. The methodology is based on formulating a differential equation that describes the relationship between blood pressure and blood flow, inspired by the Windkessel model. Additionally, a differential evolution algorithm was developed to adjust model parameters. Simulation is used to explore the model’s sensitivity and to obtain dynamic profiles of vascular compliance and peripheral resistance. Clinical implications and future work are discussed.