A 25-year-old woman arrives to the emergency department an hour after sustaining burn injuries in a house fire. She weighs 70 kilograms. She is awake but appears confused and disoriented. She complains of a severe headache and sounds stridorous. At initial exam, her temperature is 38.3 °C, blood pressure is 90/74 mmHg, heart rate is 120/min, respiratory rate is 26/min, and oxygen saturation is 89%. She has blistering, painful burns to the entire face with singed nasal hairs and carbonaceous sputum. She has burns on her entire chest, abdomen, and back, which are painless, circumferential, white, dry, and leathery. The bilateral upper extremities are also burned with painful, swollen, mottled areas with blisters that appear to have open weeping surfaces. The remainder of her skin that is not burned has a cherry-red appearance. She also has sunken eyes, a dry tongue, and slow capillary refill.