The combination of Artificial Intelligence, Machine Learning, Deep Learning, the Internet of Things, Big Data Analytics, Blockchain, and Augmented Reality/Virtual Reality is transforming healthcare by allowing for real-time monitoring, predictive analytics, improved diagnostics, and secure data management. IoT enables continuous patient monitoring, and AI and ML promote early disease detection and individualized treatments. Blockchain ensures data security, while AR/VR improves medical training and rehabilitation. Despite obstacles such as data privacy concerns, interoperability issues, and high prices, these innovations are transforming patient care, hospital efficiency, and healthcare access. This chapter investigates the effect, benefits, and limitations of these technologies, with case studies that show real-world applications in disease prediction, smart diagnostics, and data security. By giving a detailed overview of new technologies, this book chapter intends to provide useful insights into the future of smart healthcare and its transformational power.