Joining concrete elements to glass fibre-reinforced polymer (GFRP) pultruded profiles has been successfully proposed by several authors to increase the stiffness of composite structures and avoid failure due to instability phenomena. One key aspect to the success of these hybrid structures is the shear connection between the two materials, the behaviour of which is not fully understood. This paper presents experimental results of push-out tests on GFRP-concrete bolted connections and of flexural tests on full-scale hybrid GFRP – concrete beams. The interface characterization was carried out using several diameters and types of bolts, allowing to determine the average strength per bolt and the corresponding failure modes. Accounting for these results, a diameter and a type of bolt were selected for the shear connection of three hybrid beams, using various bolt spacing. Measurements recorded during bending tests up to failure showed the different stages of flexural behaviour of these beams, and the resistance and failure modes were assessed. Results showed that shear failure occurred when the bolt spacing was too large. Finally, analytical models were used to predict the behaviour of hybrid beam specimens, accounting for the recommendations of the recent Technical Specification CEN/TS 19101:2022, and a new methodology to determine the resistance of bolted connections in hybrid GFRP-concrete beams was proposed.