This chapter explores the similarities and differences in the formulation and usage of nanocosmetics and fungal-based cosmetics. The first section gives a summary of nanocosmetics, including the definition and characteristics of nanocosmetics and the types of nanomaterials used. It also delves into the formulation techniques and applications of nanocosmetics, highlighting their efficacy in skincare, haircare, and makeup products. The second section focuses on fungal-based cosmetics, introducing the concept and sources of fungal-based ingredients. It explores the bioactive substances present in fungus and their possible uses in cosmetics, emphasizing their antibacterial, anti-inflammatory, and antioxidant qualities. The section further discusses the formulation techniques used in fungal-based cosmetics, including the incorporation of fungal extracts and synergistic formulations with natural ingredients. In the third section, the similarities and differences between nanocosmetics and fungal-based cosmetics are examined. This includes a comparative analysis of active ingredients and their mechanisms of action. The formulation and manufacturing techniques utilized in both categories are explored, emphasizing the commonalities and unique challenges faced in each. Additionally, consumer usage and perception of these cosmetic categories are discussed, considering factors such as acceptance, consumer preferences, safety concerns, and market trends. In conclusion, understanding the similarities and differences between nanocosmetics and fungal-based cosmetics is crucial for formulators, researchers, and consumers. This chapter furnishes valuable insights into the formulation, application, and consumer perception of these pioneering cosmetic domains, laying the groundwork for future advancements in the field.