Coastal zones are sensitive and vulnerable areas because of the combined interaction of physical, biological, and human activities. In this sense, climate change and human factors increase the negative effects of coastal erosion, which represent a significant threat to the integrity of these ecosystems by changing their ecological services and functions. The latter has changed the way weather patterns behave along the coast, particularly in the Gulf of California, localized in northwest Mexican, where rising sea levels, stronger waves, storm surges, and expansion of human activities have led to increased coastal erosion. Furthermore, coastal urban and tourism development, exploitation of natural resources, and unsustainable fishing practices in the Anthropocene era have contributed to the recent degradation of local marine and coastal ecosystems. This chapter analyzes the negative impact on coastal ecosystems and the pattern of degradation caused by erosion in the Gulf of California. We performed a comprehensive review of the current state of the Gulf and performed a detailed analysis of the rates of coastal change using the Digital Shoreline Analysis System (DSAS) method, employing the weighted linear regression (WLR) statistic. The results show that the overall rate of change along the Gulf coast is 1.7 m/yr. Seventy percent of the coast has an erosion rate of 2.9 m/yr. The researchers identified the most prominent erosion hotspots on the northern coast of Baja California, the northern coast of Sonora, and along the coast of Sinaloa.