The research done in this paper describes integration of advanced diagnostic technologies, such as handheld ultrasound devices (HHUS) and electrochemical immunosensors, to streamline polycystic ovarian syndrome (PCOS) detection. These tools aim to provide precise, cost-effective, and user-friendly diagnostic solutions. This study also explores the potential of hybrid models incorporating machine learning techniques to analyze biomarker data more effectively, ensuring personalized and reliable diagnostic outcomes. Furthermore, the integration of wearable technology capable of monitoring stress hormones such as cortisol offers a holistic approach to managing PCOS, addressing both physiological and psychological factors contributing to the condition. These innovations not only hold the promise of advancing diagnostic efficiency but also pave the way for continuous monitoring and better management of PCOS symptoms, enhancing patient outcomes.