Family ties and corrupt exchanges often intertwine in ways that challenge conventional anti-corruption policies. In this book, I have identified multiple forms of family corruption—ranging from petty nepotism to full-blown dynastic state capture—that cut across micro, mezzo, and macro levels of society. This chapter synthesizes insights from the anti-corruption literature to examine how such measures can be tailored to the unique dynamics of family involvement. It discusses all five types of family corruption and analyzes the effectiveness of various policy responses (top-down vs. bottom-up, internal vs. external) against each. Findings indicate that one-size-fits-all strategies are often inadequate. Instead, anti-corruption interventions must account for kinship loyalties, social norms, organizational contexts, and macro-level social forces that enable family-facilitated corruption. The chapter concludes that incorporating an understanding of family networks into anti-corruption policy design is crucial for improving effectiveness.