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The P-glycoprotein (P-gp) pump is an adenosine triphosphate (ATP)-dependent pump that extrudes various compounds from protected intracellular domains. It can significantly impact the absorption and distribution pharmacokinetics of perioperative medications.

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Don’t Forget About the P-Glycoprotein Pump

  • 章节

  • 发表日期：

    2026年

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  • Catherine Marcucci,
  • Neil B. Sandson

摘要

The P-glycoprotein (P-gp) pump is an adenosine triphosphate (ATP)-dependent pump that extrudes various compounds from protected intracellular domains. It can significantly impact the absorption and distribution pharmacokinetics of perioperative medications.