Traditional treatments for gastroesophageal reflux disease (GERD) have been limited to antacid medication and antireflux surgery (ARS). However, over the course of the last two and a half decades, endoscopic therapies have emerged and matured to become viable options for patients with GERD. Endoscopic treatments include transoral incisionless fundoplication (TIF), antireflux mucosectomy (ARMS), antireflux mucosal ablation (ARMA), and radiofrequency ablation (RFA). Each of these therapies are supported by studies showing a decrease in acid exposure time and improvement in patient quality of life. The benefits of endoscopic therapies for GERD include decreased hospital length of stay and faster recovery times. While early data for endoscopic therapies is promising, more high-quality studies are need to better assess the available treatment options. At this point, given the lack of long-term and randomized prospective data, ARS remains the gold standard for treating GERD.

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Endoscopic Therapies for Gastroesophageal Reflux Disease

  • Sullivan A. Ayuso,
  • Michael B. Ujiki

摘要

Traditional treatments for gastroesophageal reflux disease (GERD) have been limited to antacid medication and antireflux surgery (ARS). However, over the course of the last two and a half decades, endoscopic therapies have emerged and matured to become viable options for patients with GERD. Endoscopic treatments include transoral incisionless fundoplication (TIF), antireflux mucosectomy (ARMS), antireflux mucosal ablation (ARMA), and radiofrequency ablation (RFA). Each of these therapies are supported by studies showing a decrease in acid exposure time and improvement in patient quality of life. The benefits of endoscopic therapies for GERD include decreased hospital length of stay and faster recovery times. While early data for endoscopic therapies is promising, more high-quality studies are need to better assess the available treatment options. At this point, given the lack of long-term and randomized prospective data, ARS remains the gold standard for treating GERD.