Bedside assessments are by their nature brief forms of sensory, motor, and cognitive testing that are often conducted within an acute care setting. These evaluations can assess generalized or more targeted cognitive functioning and can be useful to systematically assess multiple cognitive domains and monitor cognitive changes over time. Where the measures commonly used during these assessments are more easily repeatable than extensively standardized neuropsychological batteries, they lack the statistical precision of extensively standardized tests using large normative group data for comparison. Additionally, compared to more comprehensive evaluations, a bedside assessment offers unique challenges, including fluctuating or rapidly improving cognition and difficulty with environmental distractions during assessment. Further complicating these brief consultative assessments, a clinical neuropsychologist may need to explain the limitations of such a brief assessment to avoid the misperception that a patients’ condition is stable or a brief clinical assessment has the precision of a comprehensive neuropsychological evaluation. This chapter discusses the process of conducting a beside assessment, the importance of an ordered approach to neuropsychological assessment via the prerequisite model of hierarchical organization of cognition, and provides a brief assessment method that can be used when gross rapid assessment is appropriate.