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This paper provides a brief overview of the applications of 3D bioprinting technology in cancer cell-based therapies. First, we conducted a bibliometric study to examine the number of papers published from 2014 to 2024. From the collected manuscripts, we created keyword maps to gain a general understanding of the research on bioprinting and narrow the focus to cancer cell-based therapy. We identify three key areas in which bioprinting technology has been applied: (i) application and controlled cell delivery, (ii) advanced 3D models, and (iii) platforms for enhancing therapeutic cells. The selected papers are classified into T cells, NK cells, and other cell types, and are discussed in detail. This review highlights the current progress and challenges in integrating bioprinting with cancer immunotherapies. Finally, we suggest potential future directions for leveraging this technology to improve the effectiveness of cancer treatments.

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A Brief Look at 3D Bioprinting Application in Cancer Cell-Based Therapy

  • 会议论文

  • 发表日期：

    2026年

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  • Quoc-Phu Ma,
  • Jana Kotulová,
  • Jana Režnarová,
  • Agáta Kubíčková,
  • Zuzana Chyra,
  • Roman Hájek,
  • Jan Štembírek,
  • Marek Pagáč,
  • Jana Petrů

摘要

This paper provides a brief overview of the applications of 3D bioprinting technology in cancer cell-based therapies. First, we conducted a bibliometric study to examine the number of papers published from 2014 to 2024. From the collected manuscripts, we created keyword maps to gain a general understanding of the research on bioprinting and narrow the focus to cancer cell-based therapy. We identify three key areas in which bioprinting technology has been applied: (i) application and controlled cell delivery, (ii) advanced 3D models, and (iii) platforms for enhancing therapeutic cells. The selected papers are classified into T cells, NK cells, and other cell types, and are discussed in detail. This review highlights the current progress and challenges in integrating bioprinting with cancer immunotherapies. Finally, we suggest potential future directions for leveraging this technology to improve the effectiveness of cancer treatments.