With the goal of understanding contributions from developing countries, this study examines the global research landscape on Industry 4.0 (IR4.0) and Open Innovation (OI) through bibliometric analysis. It uses VOS viewer and RStudio to study publications lifecycle, geographical spread, international collaboration, and trends. From 2015 to 2023, research reports on OI and IR 4.0 were analyzed quantitatively to measure publication growth. The analysis assesses publication volume per country or region and co-authorship networks to evaluate global collaboration. The study reveals a significant acceleration in publications from 2020 as well as showing that Poland, Italy, Brazil and China have begun to publish significantly more articles focused on open innovation and IR 4.0. Significant increase in research output in emerging economies, particularly in Latin America and Asia. Co-authorship resulted in significant relationships between developed countries and Latin countries such as Brazil, Malaysia, Saudi Arabia, and other emerging economies. These relationships emphasize the urgency of foreign collaboration in digital transformation and innovation. The cited results highlight the international collaborations that developing countries ought to engage in to facilitate the acceptance of IR 4.0 and Open Innovation. These partnerships allow firms to obtain and utilize sophisticated technologies and knowledge externally, mitigating the lack of digital maturity and fostering innovation. This paper provides an unusual bibliometric analysis of IR 4.0 and OI with special attention to developing countries and their contribution to collaborative science and technology innovation in the region.