Astrocyte role in synaptic transmission is not limited only to neurotransmitter homeostasis. It include regulation, modulation and participation in short and long-term synaptic plasticity. Astrocyte network in vertebrates central neural system and in spinal cord participate in adaptation behavior and learning. Calcium is one of the key signaling molecule in many cells including neurons and astrocytes. Calcium waves in astrocytes induced by endoplasmic reticulum calcium storage release are proposed to influence on information processing and adaptation in neural networks across the brain. Large scale modeling experiments that can demonstrate the waves contribution in information processing require assembly of a tripartite biophysical model from known fragments and further reduction or simplification to perform large scale modeling experiments. Endoplasmic reticulum calcium release is triggered by inositol-1,4,5-triphosphate receptor. The ryanodine receptor is calcium-dependent and opens later, but it greatly increase calcium wave amplitude. The ryanodine receptor is intensively studied in myocytes and cardiomyocytes and several Markov models are already developed for the receptor dynamics reconstruction. Despite that, ryanodine receptors in neurons and astrocytes can differ, in general, their dynamics is similar. We reproduced five known ryanodine receptors Markov models and compared them in a tripartite synapse model where astrocyte calcium waves are reproduced. Due to different models dynamics we normalized open probability function relative to one reference model. The normalization allowed us to reproduce calcium waves and qualitatively compare the ryanodine receptors models.