In order to build predictions of the FD event rate in a PRISM oscillation measurement, it is necessary to accurately model the neutrino flux, neutrino interactions on nuclear targets and the near and far detectors. In particular, the PRISM method relies upon an accurate flux model to correctly combine the ND off-axis measurements. The models used in the analysis are subject to systematic uncertainties that affect the precision of the oscillation measurement. Systematic uncertainties are implemented as parameters of the models that, when varied, alter the components of the analysis that are derived from the MC simulation. This includes the ND and FD backgrounds, the FD flux-matching correction, the smearing matrices, the selection efficiencies and the linear combination coefficient calculation.