Liver transplantation (LT) is a rapidly evolving field. Despite innovative approaches to increase organ availability, such as using organs from donors after circulatory death (DCD), live donors, and extended criteria grafts, the gap between supply and demand persists, driven by expanding indications for LT. At the same time, more patients are considered eligible for transplantation, such as patients who have abstained from alcohol for less than 6 months and patients with greater comorbidities. Thus, the mortality rate of patients on transplant waiting lists has continued to rise worldwide. As the demographics of transplant candidates change with the aging population, it is imperative to have accurate screening and management strategies (Table 3.1) to optimize transplant outcomes and ensure the effective use of limited organs.