Intensification of technological processes and improvement of technical and technological characteristics of functional surfaces are priority tasks in modern engineering. The use of femtosecond laser structuring of stainless-steel surface is a perspective method of surface modification in order to endow them with innovative properties. The study considers issues related to the formation of modified surfaces with a high degree of hydrophobicity and hydrophilicity. The relationship between the contact angle of water droplet and the roughness of microstructured surface is discussed. The role of graphene oxide in stabilising the wettability properties of AISI 321 steel is substantiated. The results of the study can be used for future development of laser texturing processes for metals using femtosecond pulse duration lasers for various applications including wettability modification. The practical value of the research is to study the process of formation of stable hydrophobic and hydrophilic properties of stainless-steel surface processed with fs-structuring method by implantation of graphene oxide with fs-radiation.