The air permeability of a building and its functional units is important both in terms of reducing energy consumption during building operation and in ensuring physiological and comfortable conditions for human occupancy. Reducing the air permeability of buildings through the use of very dense thermal insulation elements that are poorly permeable to air has serious consequences for indoor air quality due to increased concentrations of pollutants. In this case, the lack of proper ventilation of the premises leads to a deterioration in sanitary and hygienic conditions in the premise, so it is advisable to additionally provide monitor the microclimate parameters. In this paper is presented a complex approach to monitoring of air pollution in premises and permeability of buildings. Results of experimental studies of the air exchange intensity are presented, taking into account the indoor air quality of the most common pollutants such as fine dust, formaldehyde, ozone, nitrogen dioxide, carbon monoxide and carbon dioxide.