The Mediterranean region has experienced significant impacts from climate change in recent years, with increasing temperatures and frequent heatwaves affecting both energy consumption and indoor overheating risks. This study numerically investigated various cooling technologies (green roof, blinds, advanced windows, ventilative cooling, air conditioning and their combinations) applied to the most common residential building typology in Catalonia under present and future climatic conditions. The analysis is performed both at the whole-building level and for individual zones within building. Typical meteorological years and heatwave conditions for a pre-coastal Mediterranean climate city (Manresa) have been created for three time periods, Present, Mid Future and Long Future, using dynamical downscaled Regional Climate Models based on IPCC scenarios. Resilience was assessed through indicators that account for the relationship between indoor overheating severity and outdoor climatic conditions. Additionally, thermal comfort and survivability have been examined, considering occupant’s perceptions related to indoor air temperature and humidity levels. Findings indicate that while the baseline building exhibits overall resilience, apartments on the upper floors remain vulnerable under extreme climate conditions. Implementing cooling technologies significantly improves resilience and indoor survivability, though their effectiveness declines in future scenarios. The study underscores the limitations of passive cooling measures over time and suggests that a hybrid approach integrating passive and active systems is required to ensure long-term thermal comfort and resilience.