Dental fluorosis alters the appearance of tooth enamel, with severity dependent on factors such as exposure time and type of intake (ingested vs. inhaled), weight, physical activity, nutrition, bone growth and metabolic function. Optimal fluoride dosage ranges from 0.05–0.07 mg F/Kg body weight. Various indices describe the clinical manifestations of dental fluorosis, which is also a cosmetic concern in addition to functional restoration. Patients desire an attractive smile, leading to treatment options such as bleaching, enamel microabrasions, and veneers. Several reports have analyzed the social implications of dental fluorosis and identified a correlation between its clinical manifestation and mental well-being. The social norm mandates beautiful teeth and when it deviates from that there are greater risks of social rejection and ridicule. Recent studies have focused on assessing the severity of dental fluorosis and its impact on an individual's quality of life and society. Further investigations have led to the development of a strategy to evaluate dental fluorosis’ effect on daily life, known as OHRQoL. Dental fluorosis can significantly impact a person's OHRQoL by damaging their self-esteem and hindering their ability to perform daily activities such as eating, speaking, and smiling, as well as activities of daily living such as work, school, and family interactions. There are various standardized questionnaires or scales used to measure OHRQ. Over time, researchers have developed quality of life instruments specifically tailored to oral health, and the number of these instruments continues to increase rapidly to meet the need for more specific measures.