This chapter introduces Contextually Responsive Intersectional Systems (CRIS), a leadership framework developed at the intersection of continuous improvement science and intersectionality. Emerging from an exploration of educational leadership within shifting political climates and the limitations of traditional accountability-driven improvement models, CRIS reimagines systems transformation by centering those most historically and structurally impacted. The framework offers a set of dimensions, leadership practices, and data anchors designed to support teams in redesigning policies, practices, and structures through a justice-driven lens. CRIS is rooted in three interconnected and adaptive pillars: data, co-design, and reform. These pillars guide leaders in contextualizing inequities, surfacing system design flaws, and engaging in inclusive, iterative improvement cycles. Leaders operating within CRIS adopt a stance of criticality and contextual sensitivity, integrating lived experiences and community knowledge into systemic decision-making processes. Through Contextually Responsive Intersectional Analysis, CRIS leaders illuminate disparities and drive transformation that is equity-centered and action-oriented. This chapter explores how CRIS functions in practice and the ways it disrupts traditional leadership models. Ultimately, CRIS offers a vision for leadership that is not only responsive to context but committed to fundamentally reshaping educational systems in pursuit of justice, inclusion, and sustained improvement.