Attention Deficit Hyperactivity Disorder (ADHD) is a behavioral condition characterized by the difficulty of persisting in one activity, as well as focusing and controlling impulses. Currently, the neurobiological aspects of ADHD have received growing attention. Part of these studies suggests an essential role of the dopaminergic system, which has also been described as the central nervous system’s “attentional hub,” connecting all major sensory systems. The inclusion of ADHD in the sensory processing disorder approximately two decades ago mediated the link between inattention and misdirected sensory processing in the human brain. Unfortunately, it is not easy to translate findings from basic research into clinical outcomes. It was not possible to include ADHD in the new diagnostic category “sensory processing disorder” in ICD-11 because the assault on the sensory systems by histamine during “allergic” episodes is not described as a pathognomonic core mental symptom in both major behavioral checklist types.