Quality control (QC) has long been considered essential to guarantee the reliability of neuroimaging studies. It is particularly important for fetal brain MRI, where acquisitions and image processing techniques are less standardized than in adult imaging. In this work, we focus on automated quality control of super-resolution reconstruction (SRR) volumes of fetal brain MRI, an important processing step where multiple stacks of thick 2D slices are registered together and combined to build a single, isotropic and artifact-free T2 weighted volume. We propose \(\text {FetMRQC}_{\text {SR}}\) , a machine-learning method that extracts more than 100 image quality metrics to predict image quality scores using a random forest model. This approach is well suited to a problem that is high dimensional, with highly heterogeneous data and small datasets. We validate \(\text {FetMRQC}_{\text {SR}}\) in an out-of-domain (OOD) setting and report high performance (ROC AUC = 0.89), even when faced with data from an unknown site or SRR method. We also investigate failure cases and show that they occur in \(45\%\) of the images due to ambiguous configurations for which the rating from the expert is arguable. These results are encouraging and illustrate how a non deep learning-based method like \(\text {FetMRQC}_{\text {SR}}\) is well suited to this multifaceted problem. Our tool, along with all the code used to generate, train and evaluate the model are available at https://github.com/Medical-Image-Analysis-Laboratory/fetmrqc_sr .

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Automatic Quality Control in Multi-centric Fetal Brain MRI Super-Resolution Reconstruction

  • Thomas Sanchez,
  • Vladyslav Zalevskyi,
  • Angeline Mihailov,
  • Gerard Martí Juan,
  • Elisenda Eixarch,
  • Andras Jakab,
  • Vincent Dunet,
  • Mériam Koob,
  • Guillaume Auzias,
  • Meritxell Bach Cuadra

摘要

Quality control (QC) has long been considered essential to guarantee the reliability of neuroimaging studies. It is particularly important for fetal brain MRI, where acquisitions and image processing techniques are less standardized than in adult imaging. In this work, we focus on automated quality control of super-resolution reconstruction (SRR) volumes of fetal brain MRI, an important processing step where multiple stacks of thick 2D slices are registered together and combined to build a single, isotropic and artifact-free T2 weighted volume. We propose \(\text {FetMRQC}_{\text {SR}}\) , a machine-learning method that extracts more than 100 image quality metrics to predict image quality scores using a random forest model. This approach is well suited to a problem that is high dimensional, with highly heterogeneous data and small datasets. We validate \(\text {FetMRQC}_{\text {SR}}\) in an out-of-domain (OOD) setting and report high performance (ROC AUC = 0.89), even when faced with data from an unknown site or SRR method. We also investigate failure cases and show that they occur in \(45\%\) of the images due to ambiguous configurations for which the rating from the expert is arguable. These results are encouraging and illustrate how a non deep learning-based method like \(\text {FetMRQC}_{\text {SR}}\) is well suited to this multifaceted problem. Our tool, along with all the code used to generate, train and evaluate the model are available at https://github.com/Medical-Image-Analysis-Laboratory/fetmrqc_sr .