The illicit trafficking of cultural heritage represents a significant global challenge, exacerbated by digital technologies that facilitate unauthorised trade while offering new protection opportunities. The ANCHISE project addresses these challenges through a suite of six innovative, complementary tools designed to enhance the detection, prevention, and investigation of cultural property trafficking. This paper presents these integrated tools, combining monitoring, authentication, analysis, matching, data fusion and standardisation technologies, with a strong focus on interoperability, and their real-world implementation across varied operational environments. The paper details the technological architecture of each tool, discuss implementation challenges across varied operational environments, and evaluate their performance through stakeholder feedback. Developed through collaborative efforts between law enforcement agencies, cultural heritage professionals, and technical experts, the ANCHISE toolset demonstrates promising capabilities in transforming dispersed, heterogeneous data into actionable intelligence and resources for protection of cultural heritage. The paper concludes with an assessment of the technological readiness levels achieved and outlines future development pathways to enhance the interoperability of these digital solutions for safeguarding our collective cultural heritage.