Connected and automated vehicles have been developed using vehicle-to-infrastructure (V2I) and vehicle-to-vehicle (V2V) communication. Despite these technological advancements, safety remains a concern, particularly with cruise control, which, although highly accurate and responsive compared to human drivers, still poses risks. This study aims to design a Cruise Control Vibration Deactivation Management System (CCVDMS) by investigating engineering failures that could endanger both the driver and the surrounding environment. Failure Modes and Effects Analysis (FMEA) and Risk Priority Number (RPN) methodologies were applied to identify potential failures associated with high-level vibrations. These vibrations vary depending on road profiles, making it difficult for sensors to detect vibration intensity consistently across different surfaces. The RPN results indicated that speed humps, gravel roads, and road shoulders are the most hazardous profiles. The proposed CCVDMS uses real-time vibration monitoring to automatically disengage cruise control in dangerous situations, with a vibration threshold set at approximately 0.4 m/s2.