The COVID-19 pandemic highlighted the urgency of having adequate finances as central to pandemic preparedness, particularly in Africa but also globally. The pandemic exposed the general lack of finance, as well as systematic and effective strategies for preparing for pandemics. It became clear that particularly Africa’s faith-based organizations (FBOs), governments, and others were not adequately prepared to provide effective responses to pandemics. In particular, the significant cuts in financial support to Africa (and the Global South more generally) by foreign governments highlight the vulnerability that emerges from relying on external support. This chapter explores the urgency of capacitating faith-based organizations in Africa financially as part of the overall strategy of health promotion and navigating future pandemics more effectively. Drawing lessons from the vaccine nationalism that was witnessed during the COVID-19 pandemic and the dramatic reduction in funding by governments from the Global North, the chapter maintains that it is critical for FBOs in Africa to mobilize resources from within the continent. The chapter highlights how the dependence on external funding deepens the vulnerability of most FBOs in Africa. This chapter identifies the financing of African FBOs as being particularly strategic to their capacity to promote human flourishing. It reflects on potential sources of funding within Africa, challenges to accessing these resources, and proposes some solutions. Overall, the chapter underscores the urgency of African FBOs in the health sector securing funding in Africa to meet Africa’s challenges.