Pregnancy is a period that is associated with changes occurring in the endocrinological, immunological, metabolic, and vascular systems mainly influencing the skin and other organs on a wide range of spectrum. Nearly, more than 90% of women have significant and complex skin changes during pregnancy term having an excessive impact on the woman’s life. The dermatoses of pregnancy represent a heterogeneous group of skin diseases related to pregnancy and/or the postpartum period. Most of these dermatoses of pregnancy can be treated substantially but some require intervention in the form of termination of pregnancy itself. In the current chapter, we will be discussing the current knowledge of various skin changes during pregnancy and the evaluation of the patient with pregnancy dermatoses with special emphasis on clinical features, diagnostic tests, maternal and fetal prognosis, therapy, and management.