Trees in urban green areas provide multiple ecological and social contributions when environmental conditions support their growth and vitality potential Tree development phase, responses to climate and anthropological disturbance, and competition for space (soil, air, light) influence their ability to preserve health and resist disease occurrence. This study aimed to examine the effect of the dendrometric variable, habitual defects, and special pressures of the other neighboring trees on disease occurrence in Acer platanoides L. (Norway maple) and Acer pseudoplatanus L., (sycamore maple) trees in urban environment. In 2017, researchers conducted a tree inventory and visual assessment in the historical park Ilidža, Bosnia and Herzegovina. The research revealed that the disease occurrence is more probable in middle height classes for both tree species (up to 19.5 and 22.3 m tree height, respectively). Disease occurrence on Norway maple is associated with spatial competition and broken branches, while disease occurrence on sycamore maple is associated with decay and distance to neighboring tree species. Logistic regression models reached very good specificity and sensitivity for Area Under the Curve (AUC: 0.80 and 0.79, respectively). The obtained results could be used to differentiate and prioritise measures for maintaining and protecting each tree species. The applied methodology could support the identification of the most influential habitual factors as well as spatial pressures for the prevention and reduction of disease on urban trees.