The increasing application of interactive technologies is transforming museum exhibition design from static displays to dynamic, user-centered experiences. This study proposes a spatial organization model for museum exhibitions, featuring six functional zones based on interaction characteristics and a flexible, multi-route layout structure to accommodate personalized visitor journeys. A mixed-method approach was employed, combining theoretical synthesis with case study analysis of five representative museums. The study contributes a theoretical design model for exhibition spaces, offering practical value for curators, architects, and museum designers in the context of digital transformation.