Central Bank Digital Currencies (CBDCs) have emerged as a disruptive element within the global financial system, sparking extensive debates concerning their regulation, impact on monetary policy, and financial stability. This study conducts a systematic literature review (SLR) following the PRISMA 2020 statement and the ECLIPSE framework to structure the research questions, enabling a comprehensive analysis of the primary regulatory challenges and opportunities associated with CBDCs. By examining academic literature indexed in databases such as Scopus and ScienceDirect, key issues related to cybersecurity, privacy, interoperability, and the risk of banking disintermediation are identified. The findings indicate that, while CBDCs can enhance financial inclusion and improve the efficiency of payment systems, their implementation necessitates robust regulatory frameworks to mitigate risks associated with money laundering, international governance, and the balance between oversight and privacy. In this regard, the study underscores the need to develop dynamic regulatory strategies and hybrid privacy models that ensure both security and innovation within the global financial system. The study concludes with policy recommendations aimed at facilitating the safe and efficient adoption of CBDCs without compromising financial stability or national monetary sovereignty.