Green synthesized nanotechnology offers a transformative approach to pest and disease management in agriculture, providing sustainable alternatives to conventional pesticides. This work explores the applications, mechanisms, and benefits of nanopesticides, including organic, inorganic, and hybrid systems, which improve pesticide delivery precision, reduce environmental contamination, and enhance agricultural productivity. While not centered on green synthesis methods, it emphasizes that the nanomaterials discussed can be obtained through sustainable processes outlined in previous sections of this book. Case studies illustrate the effectiveness of nanopesticides against diverse pests and pathogens, addressing challenges such as pest resistance, excessive agrochemical use, and ecological toxicity. The discussion also highlights the role of smart nanocarriers and controlled-release formulations in optimizing pesticide usage while minimizing environmental risks. Despite these advancements, significant challenges remain, such as scaling up green synthesis, ensuring regulatory compliance, and understanding long-term ecological impacts. This comprehensive perspective links the synthesis and application of nanomaterials to foster sustainable agricultural practices. By advancing research, innovation, and interdisciplinary collaboration, green synthesized nanotechnology has the potential to revolutionize crop protection while safeguarding environmental and human health division leads to a decrease in plant production. Therefore, more research is needed to investigate the effectiveness of different particles on various plant species.