Many thinkers endorse an idea that we humans should leave nature alone or somehow exercise restraint in our relations to nature. Among those thinkers, we find several who take a critical or pessimistic attitude to modernity and modern life in general and to technology, or some specific technologies like genetic engineering in particular. In this chapter, I take a constructive approach starting with an exploration of Albert Borgmann’s idea of focal practices. I side with Paul B. Thompson in suggesting that agricultural systems offer some potential areas for such focal practices. I argue that even highly engineered environments should contain ‘pockets of focality’ and that those may provide ‘stepping stones’ from which a system can be changed. Finally, I argue that there is room for implementing some of these elements within a context of responsible research and innovation, for instance in the form of ethics committees for food and agricultural issues.