The prospects and relevance of increasing the uniformity of the mixture in static mixers used in the construction industry and other industries for mixing non-Newtonian fluids are considered. The advantages of static mixers are considered, one of which is the possibility of their integration into existing production lines. The purpose of the study is to identify and analyze the design and technological parameters of the mixing elements that affect the uniformity coefficient of the mixture. It is established that the uniformity coefficient of the mixture depends on the diameter of the mixing chamber, the number and distance between the inserts, the shape and number of holes in them, as well as the pressure of the liquid supply. Their effect on the uniformity coefficient was revealed by regression analysis using a two-factor central composite rotating second-order plan (CCRP 22) on a full-scale model of a static mixer with Maltese cross inserts. Computer hydrodynamic modeling of the mixing process in a semi-industrial sample was carried out to determine its operability and efficiency. The geometric parameters of a semi-industrial sample were determined, providing the highest coefficient of uniformity (K ≈100%): with a mixing chamber diameter of D = 200 mm, its length L = 500 mm with 7 perforated inserts, the distance between which is l = 71 mm, or with D = 200 mm, L = 370 mm and l = 45 mm.